USP54 and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		USP54	EIF4E2
Description		ubiquitin specific peptidase 54	eukaryotic translation initiation factor 4E family member 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Deubiquitination	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS			Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		21 interacting genes: ARID5B ATN1 ATXN1 CDK19 CFAP70 CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 EIF4E2 FAM149B1 FUT11 HK1 MSS51 MSX2 NXT2 PLCD1 SAMD8 TTYH1 UBC	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		159195	9470
HPRD ID		15641	05798
Ensembl ID		ENSG00000166348	ENSG00000135930
Uniprot IDs		B7Z7X1 Q70EL1	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs			2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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