USP54 and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 19302785)
8

Data Source:
BioGRID (pull down)

		USP54	CHMP4C
Description		ubiquitin specific peptidase 54	charged multivesicular body protein 4C
Image		No pdb structure
GO Annotations	Cellular Component		ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Deubiquitination	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell
Pathways			Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS			Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		21 interacting genes: ARID5B ATN1 ATXN1 CDK19 CFAP70 CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 EIF4E2 FAM149B1 FUT11 HK1 MSS51 MSX2 NXT2 PLCD1 SAMD8 TTYH1 UBC	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		159195	92421
HPRD ID		15641	18135
Ensembl ID		ENSG00000166348	ENSG00000164695
Uniprot IDs		B7Z7X1 Q70EL1	Q96CF2
PDB IDs			3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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