RPH3A and RAB3A

Number of citations of the paper that reports this interaction (PubMedID 10025402)
90

Data Source:
HPRD (in vitro, in vivo)

		RPH3A	RAB3A
Description		rabphilin 3A	RAB3A, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane Protein-containing Complex Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane	Acrosomal Vesicle Cell Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Axon Secretory Granule Membrane Cytoplasmic Vesicle Vesicle Protein-containing Complex Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane Extracellular Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Rab GTPase Binding Phosphate Ion Binding Protein-containing Complex Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GTP-dependent Protein Binding Myosin V Binding GDP-dissociation Inhibitor Binding ATPase Binding
	Biological Process	Intracellular Protein Transport Spontaneous Neurotransmitter Secretion	Plasma Membrane Repair Respiratory System Process Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Mitochondrion Organization Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Dopamine Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Regulation Of Exocytosis Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Rab Protein Signal Transduction Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Neutrophil Degranulation Post-translational Protein Modification Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Protein Localization To Plasma Membrane Synaptic Vesicle Clustering Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 26426971) Chloride levels ( 29403010) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 29403010) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Urate levels ( 31578528)	Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
Interacting Genes		10 interacting genes: ADD2 CASK GCH1 NRXN1 RAB15 RAB27A RAB3A RAB3B RAB8A YWHAH	24 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML DMXL2 ECSIT EGFR MAST1 PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SYTL4 SYTL5
Entrez ID		22895	5864
HPRD ID		15273	01535
Ensembl ID		ENSG00000089169	ENSG00000105649
Uniprot IDs		A0A024RBK6 Q9Y2J0	A0A024R7I7 P20336
PDB IDs
Enriched GO Terms of Interacting Partners?
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