RAB3A and AP1M2

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		RAB3A	AP1M2
Description		RAB3A, member RAS oncogene family	adaptor related protein complex 1 subunit mu 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cell Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Axon Secretory Granule Membrane Cytoplasmic Vesicle Vesicle Protein-containing Complex Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane Extracellular Vesicle	Golgi Membrane Cell Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GTP-dependent Protein Binding Myosin V Binding GDP-dissociation Inhibitor Binding ATPase Binding	Protein Binding
	Biological Process	Plasma Membrane Repair Respiratory System Process Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Mitochondrion Organization Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Dopamine Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Regulation Of Exocytosis Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Rab Protein Signal Transduction Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Neutrophil Degranulation Post-translational Protein Modification Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Protein Localization To Plasma Membrane Synaptic Vesicle Clustering Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair	Protein Targeting Vesicle Targeting Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414)
Interacting Genes		24 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML DMXL2 ECSIT EGFR MAST1 PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SYTL4 SYTL5	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		5864	10053
HPRD ID		01535	06296
Ensembl ID		ENSG00000105649	ENSG00000129354
Uniprot IDs		A0A024R7I7 P20336	Q53GI5 Q9Y6Q5
PDB IDs
Enriched GO Terms of Interacting Partners?
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