RAB3A and DMXL2

Number of citations of the paper that reports this interaction (PubMedID 11809763)
18

Data Source:
HPRD (in vivo)

		RAB3A	DMXL2
Description		RAB3A, member RAS oncogene family	Dmx like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cell Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Axon Secretory Granule Membrane Cytoplasmic Vesicle Vesicle Protein-containing Complex Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane Extracellular Vesicle	Extracellular Space Cell Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane RAVE Complex Neuronal Dense Core Vesicle
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GTP-dependent Protein Binding Myosin V Binding GDP-dissociation Inhibitor Binding ATPase Binding	Rab GTPase Binding
	Biological Process	Plasma Membrane Repair Respiratory System Process Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Mitochondrion Organization Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Dopamine Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Regulation Of Exocytosis Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Rab Protein Signal Transduction Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Neutrophil Degranulation Post-translational Protein Modification Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Protein Localization To Plasma Membrane Synaptic Vesicle Clustering Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair	Vacuolar Acidification
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)	BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) C-reactive protein levels ( 30388399) Intelligence (MTAG) ( 29326435)
Interacting Genes		24 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML DMXL2 ECSIT EGFR MAST1 PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SYTL4 SYTL5	2 interacting genes: MTNR1B RAB3A
Entrez ID		5864	23312
HPRD ID		01535	10188
Ensembl ID		ENSG00000105649	ENSG00000104093
Uniprot IDs		A0A024R7I7 P20336	A0A024R5V2 Q8TDJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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