EEF1G and HMOX2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		EEF1G	HMOX2
Description		eukaryotic translation elongation factor 1 gamma	heme oxygenase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Cell Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding
	Biological Process	Translational Elongation Response To Virus	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis
Pathways		Eukaryotic Translation Elongation	Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs			NADH Stannsoporfin
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Erectile dysfunction ( 30583798)
Interacting Genes		88 interacting genes: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LZTS1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	35 interacting genes: A2M APP ATP5F1B BLOC1S2 CEBPZ CEP126 COPS6 CSNK2A1 EEF1G EIF3C GIT1 GPRASP1 HAP1 IMMT INPP5K ITFG1 JADE1 KCNMA1 LMNA LRIF1 MARK3 MED31 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 RBBP4 SETDB1 SHC1 SKA2 SNX5 SNX7 ZFP28 ZNF746
Entrez ID		1937	3163
HPRD ID		11745	00783
Ensembl ID		ENSG00000254772	ENSG00000103415
Uniprot IDs		P26641 Q53YD7	A0A087WT44 B3KSE0 P30519
PDB IDs		1PBU 5DQS 5JPO	2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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