HMOX2 and BLOC1S2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		HMOX2	BLOC1S2
Description		heme oxygenase 2	biogenesis of lysosomal organelles complex 1 subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs		NADH Stannsoporfin
Diseases
GWAS		Erectile dysfunction ( 30583798)
Interacting Genes		35 interacting genes: A2M APP ATP5F1B BLOC1S2 CEBPZ CEP126 COPS6 CSNK2A1 EEF1G EIF3C GIT1 GPRASP1 HAP1 IMMT INPP5K ITFG1 JADE1 KCNMA1 LMNA LRIF1 MARK3 MED31 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 RBBP4 SETDB1 SHC1 SKA2 SNX5 SNX7 ZFP28 ZNF746	15 interacting genes: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASHC1
Entrez ID		3163	282991
HPRD ID		00783	12526
Ensembl ID		ENSG00000103415	ENSG00000196072
Uniprot IDs		A0A087WT44 B3KSE0 P30519	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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