EEF1D and EPRS1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		EEF1D	EPRS1
Description		eukaryotic translation elongation factor 1 delta	glutamyl-prolyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Cytoplasm Cytosol Plasma Membrane Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Glutamate-tRNA Ligase Activity Proline-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding RNA Stem-loop Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Ionizing Radiation	TRNA Aminoacylation For Protein Translation Glutamyl-tRNA Aminoacylation Prolyl-tRNA Aminoacylation Negative Regulation Of Translation Cellular Response To Insulin Stimulus Protein-containing Complex Assembly Cellular Response To Interferon-gamma Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways		Eukaryotic Translation Elongation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation tRNA modification in the nucleus and cytosol
Drugs			Glutamic Acid L-Proline '5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine '5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine
Diseases
GWAS		Schizophrenia ( 31268507)
Interacting Genes		38 interacting genes: APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	12 interacting genes: AIMP2 ARL4D DUS2 EEF1D ESR1 HSP90AA1 IARS1 NEDD4 NELFCD RARS1 SYNCRIP TAB1
Entrez ID		1936	2058
HPRD ID		00560	00703
Ensembl ID		ENSG00000104529	ENSG00000136628
Uniprot IDs		B2RAR6 D3DWK1 P29692	P07814
PDB IDs		2MVM 2MVN 2N51 5JPO	1FYJ 4HVC 4K86 4K87 4K88 5A1N 5A34 5A5H 5BMU 5V58 5VAD 5Y6L 6IY6
Enriched GO Terms of Interacting Partners?
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