TLE5 and KRTAP10-8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TLE5	KRTAP10-8
Description		TLE family member 5, transcriptional modulator	keratin associated protein 10-8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex	Cytosol Keratin Filament
	Molecular Function	Transcription Corepressor Activity Protein Binding Repressing Transcription Factor Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Multicellular Organism Development Animal Organ Morphogenesis Negative Regulation Of Gene Expression Wnt Signaling Pathway Cellular Response To Extracellular Stimulus Negative Regulation Of Protein Binding Regulation Of Growth Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Anoikis	Keratinization
Pathways		Repression of WNT target genes	Keratinization
Drugs
Diseases
GWAS
Interacting Genes		165 interacting genes: ABI2 AEN AMH AR ARHGAP32 ATN1 ATP6V0D1 BAHD1 BCL6 BHLHE40 BIRC7 BYSL C1orf109 C1orf216 C1orf94 CABP4 CALCOCO2 CAPN1 CARD9 CCDC57 CCL7 CCNJL CCNK CFAP206 CIB3 CPSF7 CRACR2A CRX DCUN1D1 DDX6 DGCR6 DIP2A DNMT3L DVL2 EAF1 EAF2 EIF4E2 FAM124A FAM124B FANCG FBF1 FBLN1 FHL3 FOXP2 FRS3 FSD2 GABARAP GFAP GFI1B GLRX3 GOLGA2 GORASP2 GRAP2 GRB2 GTF2E1 HCN2 HGS HMGB1 HNF1A HNRNPF HNRNPH2 HNRNPLL HOMEZ IKZF3 KANK2 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 L3MBTL2 LDOC1 LINC00526 LMO1 LMO2 LMO4 LSM2 MAGOHB MAPK14 MBNL1 MED31 MED4 MFAP1 MIA2 MKRN3 MLH1 MLX MORF4L2 MSX1 MTUS2 MVP MYO15B NAB2 NCDN NEK6 NOTCH2NLA NTAQ1 NUDT22 OLIG3 OSGIN1 PARVG PHKB POU2F1 PPP1R16A PPP1R16B PRDM1 PRKAA1 PRKAA2 PRKAB2 PRPF31 PRR3 PSMF1 PTRH2 QARS1 RBM10 RBPMS REL RELA RFX6 RHOXF2 RIMBP3 RNF31 RPL18A RUNX1 SCNM1 SDCBP SH3GL3 SIX1 SIX2 SIX3 SIX6 SKIL SMAD3 SMARCB1 SNCAIP SNRPC SOX5 SRPK2 STK16 STX11 SUPT5H TBX3 TCF4 TMCC2 TNS2 TRAF1 TRAF2 TRIM26 TRIM27 TRIM41 TSC22D4 TSGA10 TSSK3 U2AF2 UBE2H UBXN11 VPS37B VPS37C ZBTB24 ZGPAT ZNF576	165 interacting genes: - ACY3 ADAMTSL3 ADAMTSL4 AEN ALDH3B1 ALPI AMMECR1 APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 CARHSP1 CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MOBP MTA1 MXI1 NAB2 NAXD NECTIN3 NOTCH2NLA NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SHFL SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPACA9 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TLE5 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21
Entrez ID		166	386681
HPRD ID		02556	11194
Ensembl ID		ENSG00000104964	ENSG00000187766
Uniprot IDs		Q08117 Q8WY48	P60410
PDB IDs
Enriched GO Terms of Interacting Partners?
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