TLE5 and GORASP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TLE5	GORASP2
Description		TLE family member 5, transcriptional modulator	golgi reassembly stacking protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding Repressing Transcription Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Multicellular Organism Development Animal Organ Morphogenesis Negative Regulation Of Gene Expression Wnt Signaling Pathway Cellular Response To Extracellular Stimulus Negative Regulation Of Protein Binding Regulation Of Growth Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Anoikis	Organelle Organization Golgi Organization Spermatogenesis Cell Differentiation Response To Endoplasmic Reticulum Stress Establishment Of Protein Localization To Plasma Membrane Organelle Assembly
Pathways		Repression of WNT target genes	Golgi Cisternae Pericentriolar Stack Reorganization
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Interacting Genes		165 interacting genes: ABI2 AEN AMH AR ARHGAP32 ATN1 ATP6V0D1 BAHD1 BCL6 BHLHE40 BIRC7 BYSL C1orf109 C1orf216 C1orf94 CABP4 CALCOCO2 CAPN1 CARD9 CCDC57 CCL7 CCNJL CCNK CFAP206 CIB3 CPSF7 CRACR2A CRX DCUN1D1 DDX6 DGCR6 DIP2A DNMT3L DVL2 EAF1 EAF2 EIF4E2 FAM124A FAM124B FANCG FBF1 FBLN1 FHL3 FOXP2 FRS3 FSD2 GABARAP GFAP GFI1B GLRX3 GOLGA2 GORASP2 GRAP2 GRB2 GTF2E1 HCN2 HGS HMGB1 HNF1A HNRNPF HNRNPH2 HNRNPLL HOMEZ IKZF3 KANK2 KIFC3 KRT13 KRT15 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 L3MBTL2 LDOC1 LINC00526 LMO1 LMO2 LMO4 LSM2 MAGOHB MAPK14 MBNL1 MED31 MED4 MFAP1 MIA2 MKRN3 MLH1 MLX MORF4L2 MSX1 MTUS2 MVP MYO15B NAB2 NCDN NEK6 NOTCH2NLA NTAQ1 NUDT22 OLIG3 OSGIN1 PARVG PHKB POU2F1 PPP1R16A PPP1R16B PRDM1 PRKAA1 PRKAA2 PRKAB2 PRPF31 PRR3 PSMF1 PTRH2 QARS1 RBM10 RBPMS REL RELA RFX6 RHOXF2 RIMBP3 RNF31 RPL18A RUNX1 SCNM1 SDCBP SH3GL3 SIX1 SIX2 SIX3 SIX6 SKIL SMAD3 SMARCB1 SNCAIP SNRPC SOX5 SRPK2 STK16 STX11 SUPT5H TBX3 TCF4 TMCC2 TNS2 TRAF1 TRAF2 TRIM26 TRIM27 TRIM41 TSC22D4 TSGA10 TSSK3 U2AF2 UBE2H UBXN11 VPS37B VPS37C ZBTB24 ZGPAT ZNF576	71 interacting genes: AAMDC ACY3 AGPS APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA RPS6KA1 SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TLE5 TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148
Entrez ID		166	26003
HPRD ID		02556	08303
Ensembl ID		ENSG00000104964	ENSG00000115806
Uniprot IDs		Q08117 Q8WY48	Q9H8Y8
PDB IDs			3RLE 4EDJ
Enriched GO Terms of Interacting Partners?
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