ADORA2B and TPD52L2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ADORA2B	TPD52L2
Description		adenosine A2b receptor	TPD52 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	G Protein-coupled Adenosine Receptor Activity Protein Binding	RNA Binding Catalytic Activity
	Biological Process	Activation Of MAPK Activity Adenosine Receptor Signaling Pathway Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity JNK Cascade Excretion Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of CGMP-mediated Signaling Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Extracellular Stimulus Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Mast Cell Degranulation Cellular Protein Metabolic Process Relaxation Of Vascular Smooth Muscle Regulation Of Synaptic Vesicle Exocytosis
Pathways		Adenosine P1 receptors G alpha (s) signalling events Surfactant metabolism ADORA2B mediated anti-inflammatory cytokines production
Drugs		Theophylline Adenosine Enprofylline Defibrotide	Phenethyl Isothiocyanate
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Prostate cancer ( 23535732)
Interacting Genes		7 interacting genes: ADA DCC EZR NTN1 SLC9A3R2 TPD52L2 ZNF267	7 interacting genes: ADORA2B APP MAL2 SH3GLB1 TPD52 TPD52L1 TPD52L3
Entrez ID		136	7165
HPRD ID		15971	11947
Ensembl ID		ENSG00000170425	ENSG00000101150
Uniprot IDs		P29275	A0A087WYR3 A0A087WZ51 O43399 Q68E05 Q6FGS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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