ADORA2B and ZNF267

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ADORA2B	ZNF267
Description		adenosine A2b receptor	zinc finger protein 267
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Nucleus
	Molecular Function	G Protein-coupled Adenosine Receptor Activity Protein Binding	DNA Binding DNA-binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Activation Of MAPK Activity Adenosine Receptor Signaling Pathway Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity JNK Cascade Excretion Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of CGMP-mediated Signaling Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Extracellular Stimulus Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Mast Cell Degranulation Cellular Protein Metabolic Process Relaxation Of Vascular Smooth Muscle Regulation Of Synaptic Vesicle Exocytosis	Regulation Of Transcription, DNA-templated Multicellular Organism Development
Pathways		Adenosine P1 receptors G alpha (s) signalling events Surfactant metabolism ADORA2B mediated anti-inflammatory cytokines production	Generic Transcription Pathway
Drugs		Theophylline Adenosine Enprofylline Defibrotide
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		7 interacting genes: ADA DCC EZR NTN1 SLC9A3R2 TPD52L2 ZNF267	4 interacting genes: ADORA2B ATP6V0A1 BCKDK EPHA7
Entrez ID		136	10308
HPRD ID		15971	06883
Ensembl ID		ENSG00000170425	ENSG00000185947
Uniprot IDs		P29275	Q14586
PDB IDs
Enriched GO Terms of Interacting Partners?
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