Search Results for: TP53

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
YY1 YY1 transcription factor
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • Estrogen-dependent gene expression
AKAP5 A-kinase anchoring protein 5
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Trafficking of AMPA receptors
  • ROBO receptors bind AKAP5
  • ROBO receptors bind AKAP5
ANXA2 annexin A2
  • Smooth Muscle Contraction
  • Neutrophil degranulation
  • Dissolution of Fibrin Clot
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • Tenecteplase
  • Fluocinolone acetonide
  • Lanoteplase
  • Artenimol
ATF3 activating transcription factor 3
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Pseudoephedrine
CDKN2C cyclin dependent kinase inhibitor 2C
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • Oncogene Induced Senescence
  • Cyclin D associated events in G1
COPS2 COP9 signalosome subunit 2
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS3 COP9 signalosome subunit 3
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS4 COP9 signalosome subunit 4
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS5 COP9 signalosome subunit 5
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS6 COP9 signalosome subunit 6
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS7A COP9 signalosome subunit 7A
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
COPS8 COP9 signalosome subunit 8
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
GPS1 G protein pathway suppressor 1
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
HSPA9 heat shock protein family A (Hsp70) member 9
  • Mitochondrial protein import
  • Regulation of HSF1-mediated heat shock response
  • Cristae formation
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
HSPB1 heat shock protein family B (small) member 1
  • VEGFA-VEGFR2 Pathway
  • AUF1 (hnRNP D0) binds and destabilizes mRNA
  • MAPK6/MAPK4 signaling
  • Extra-nuclear estrogen signaling
  • Apatorsen
  • Artenimol
  • Phenethyl Isothiocyanate
  • Distal hereditary motor neuropathies (dHMN)
KLF4 Kruppel like factor 4
  • Transcriptional regulation of white adipocyte differentiation
  • Synthesis, secretion, and deacylation of Ghrelin
  • Transcriptional regulation of pluripotent stem cells
  • FOXO-mediated transcription of cell cycle genes
MAPK10 mitogen-activated protein kinase 10
  • Oxidative Stress Induced Senescence
  • FCERI mediated MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • Activation of the AP-1 family of transcription factors
  • Minocycline
  • Pyrazolanthrone
  • Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
  • Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
  • 9-(4-Hydroxyphenyl)-2,7-Phenanthroline
  • Phosphoaminophosphonic Acid-Adenylate Ester
  • N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide
  • N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE
  • N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide
  • 4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide
  • (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime
  • (3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime
  • (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime
  • 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide
  • N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine
  • N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE
  • 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide
  • 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
  • Fostamatinib
  • Halicin
MAPK9 mitogen-activated protein kinase 9
  • Oxidative Stress Induced Senescence
  • FCERI mediated MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • Activation of the AP-1 family of transcription factors
  • Minocycline
  • N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
  • Fostamatinib
  • Halicin
MED17 mediator complex subunit 17
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
PELI1 pellino E3 ubiquitin protein ligase 1
  • Regulation of necroptotic cell death
  • Interleukin-1 signaling
  • IRAK1 recruits IKK complex
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation

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