Search Results for: STK11

139 interactions involving STK11 - serine/threonine kinase 11 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
STK11IP serine/threonine kinase 11 interacting protein
  • Neutrophil degranulation
STRADA STE20 related adaptor alpha
  • Energy dependent regulation of mTOR by LKB1-AMPK
STRADB STE20 related adaptor beta
  • Energy dependent regulation of mTOR by LKB1-AMPK
STX17 syntaxin 17
  • COPII-mediated vesicle transport
TBC1D23 TBC1 domain family member 23
TDRD7 tudor domain containing 7
TEAD2 TEA domain transcription factor 2
  • YAP1- and WWTR1 (TAZ)-stimulated gene expression
  • RUNX3 regulates YAP1-mediated transcription
THOP1 thimet oligopeptidase 1
  • Antigen processing: Ubiquitination & Proteasome degradation
THRSP thyroid hormone responsive
  • Carnitine metabolism
TNIP2 TNFAIP3 interacting protein 2
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Ovarian tumor domain proteases
TRIM25 tripartite motif containing 25
  • ISG15 antiviral mechanism
  • DDX58/IFIH1-mediated induction of interferon-alpha/beta
  • Termination of translesion DNA synthesis
  • Ovarian tumor domain proteases
  • Interferon gamma signaling
  • TRAF3-dependent IRF activation pathway
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
  • Negative regulators of DDX58/IFIH1 signaling
  • Negative regulators of DDX58/IFIH1 signaling
TRMO tRNA methyltransferase O
TSG101 tumor susceptibility 101
  • Budding and maturation of HIV virion
  • Membrane binding and targetting of GAG proteins
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
VPS72 vacuolar protein sorting 72 homolog
  • HATs acetylate histones
WT1 WT1 transcription factor
  • Transcriptional regulation of testis differentiation
  • Nephrotic syndrome and focal segmental glomerulosclerosis
  • 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
XPA XPA, DNA damage recognition and repair factor
  • Formation of Incision Complex in GG-NER
  • Dual Incision in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Dual incision in TC-NER
  • Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • AURKA Activation by TPX2
  • Regulation of localization of FOXO transcription factors
ZNF189 zinc finger protein 189
  • Generic Transcription Pathway
ZNF510 zinc finger protein 510
  • Generic Transcription Pathway

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