Search Results for: STK11

139 interactions involving STK11 - serine/threonine kinase 11 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MOB4 MOB family member 4, phocein
MOCS2 molybdenum cofactor synthesis 2
  • Molybdenum cofactor biosynthesis
  • Molybdenum cofactor biosynthesis
  • Xanthinuria
NANS N-acetylneuraminate synthase
  • Sialic acid metabolism
NAT2 N-acetyltransferase 2
  • Acetylation
NF2 neurofibromin 2
  • Regulation of actin dynamics for phagocytic cup formation
  • RHO GTPases activate PAKs
  • Malignant pleural mesothelioma
  • Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
PARD3 par-3 family cell polarity regulator
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • Tight junction interactions
PHF23 PHD finger protein 23
PLD3 phospholipase D family member 3
  • Synthesis of PG
  • Role of phospholipids in phagocytosis
PRSS50 serine protease 50
RASA1 RAS p21 protein activator 1
  • Downstream signal transduction
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • VEGFR2 mediated cell proliferation
  • Regulation of RAS by GAPs
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • RASA1-related disorders, including: Parkes-Weber slndrome; Capillary malformation-arteriovenous malformation (CM-AVM); Arteriovenous fistula (AVF)
RASSF1 Ras association domain family member 1
  • Non-small cell lung cancer
  • Bladder cancer
  • Nasopharyngeal cancer
RHOBTB2 Rho related BTB domain containing 2
  • RHOBTB2 GTPase cycle
RPS6KA5 ribosomal protein S6 kinase A5
  • ERK/MAPK targets
  • CREB phosphorylation
  • NCAM signaling for neurite out-growth
  • Recycling pathway of L1
  • CD209 (DC-SIGN) signaling
RPS6KB1 ribosomal protein S6 kinase B1
  • mTORC1-mediated signalling
S100A14 S100 calcium binding protein A14
SEPTIN9 septin 9
  • Hereditary neuralgic amyotrophy (HNA); Hereditary brachial plexus neuropathy
SMAD1 SMAD family member 1
  • Signaling by BMP
  • Ub-specific processing proteases
  • RUNX2 regulates bone development
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Interleukin-7 signaling
  • Formation of the beta-catenin:TCF transactivating complex
  • RMTs methylate histone arginines
  • Chromatin modifying enzymes
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
SOX4 SRY-box transcription factor 4
  • Deactivation of the beta-catenin transactivating complex
SPDEF SAM pointed domain containing ETS transcription factor

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