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CYTH2 |
cytohesin 2 |
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- Inositol 1,3,4,5-Tetrakisphosphate
- Formic acid
- 1D-myo-inositol 1,4,5-trisphosphate
- S,S-(2-Hydroxyethyl)Thiocysteine
- Brefeldin A
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CYTH3 |
cytohesin 3 |
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- Inositol 1,3,4,5-Tetrakisphosphate
- Inositol-(1,3,4,5,6)-Pentakisphosphate
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DNAJB6 |
DnaJ heat shock protein family (Hsp40) member B6 |
- Regulation of HSF1-mediated heat shock response
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FBP2 |
fructose-bisphosphatase 2 |
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GABRB1 |
gamma-aminobutyric acid type A receptor subunit beta1 |
- Signaling by ERBB4
- GABA receptor activation
- GABA receptor activation
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- Lorazepam
- Ethchlorvynol
- Enflurane
- Temazepam
- Butabarbital
- Butalbital
- Phenytoin
- Etomidate
- Talbutal
- Pentobarbital
- Clobazam
- Meprobamate
- Eszopiclone
- Alprazolam
- Lindane
- Metharbital
- Chlordiazepoxide
- Amoxapine
- Adinazolam
- Lamotrigine
- Medroxyprogesterone acetate
- Clorazepic acid
- Acamprosate
- Midazolam
- Flurazepam
- Isoflurane
- Primidone
- Halazepam
- Propofol
- Diazepam
- Oxazepam
- Triazolam
- Ethanol
- Methoxyflurane
- Memantine
- Clonazepam
- Methyprylon
- Halothane
- Desflurane
- Flumazenil
- Estazolam
- Sevoflurane
- Glutethimide
- gamma-Hydroxybutyric acid
- Camazepam
- Delorazepam
- Flunitrazepam
- Ethyl loflazepate
- Cloxazolam
- Bromazepam
- Clotiazepam
- Fludiazepam
- Ketazolam
- Prazepam
- Quazepam
- Cinolazepam
- Nitrazepam
- Prasterone
- Taurine
- Brotizolam
- Stiripentol
- Etizolam
- Thiocolchicoside
- Brexanolone
- Apalutamide
- Remimazolam
- Benzodiazepine
- Pinazepam
- Medazepam
- Loprazolam
- Doxefazepam
- Lormetazepam
- Nordazepam
- Oxazepam acetate
- Cinazepam
- Bentazepam
- Mexazolam
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GALNT12 |
polypeptide N-acetylgalactosaminyltransferase 12 |
- Defective GALNT12 causes colorectal cancer 1 (CRCS1)
- O-linked glycosylation of mucins
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GNAQ |
G protein subunit alpha q |
- Acetylcholine regulates insulin secretion
- Acetylcholine regulates insulin secretion
- G alpha (q) signalling events
- G alpha (q) signalling events
- ADP signalling through P2Y purinoceptor 1
- ADP signalling through P2Y purinoceptor 1
- Thromboxane signalling through TP receptor
- Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
- Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
- Thrombin signalling through proteinase activated receptors (PARs)
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GRIN2B |
glutamate ionotropic receptor NMDA type subunit 2B |
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- MECP2 regulates neuronal receptors and channels
- Activated NTRK2 signals through FYN
- Assembly and cell surface presentation of NMDA receptors
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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- Glutamic acid
- Tramadol
- Enflurane
- Atomoxetine
- Pentobarbital
- Methadone
- Secobarbital
- Meperidine
- Haloperidol
- Acamprosate
- Donepezil
- Guaifenesin
- Felbamate
- Memantine
- Phenobarbital
- Aripiprazole
- Tenocyclidine
- Prasterone
- Taurine
- Milnacipran
- EVT-101
- Lumateperone
- Acetylcysteine
- Ketobemidone
- Gavestinel
- Ifenprodil
- Magnesium acetate tetrahydrate
- Magnesium carbonate
- Esketamine
- Esketamine
- Fluciclovine (18F)
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IL13RA2 |
interleukin 13 receptor subunit alpha 2 |
- Interleukin-4 and Interleukin-13 signaling
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IL24 |
interleukin 24 |
- Interleukin-20 family signaling
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IL3 |
interleukin 3 |
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- RAF/MAP kinase cascade
- RUNX1 regulates transcription of genes involved in interleukin signaling
- Interleukin receptor SHC signaling
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- Amlexanox
- Zinc
- Polaprezinc
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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IRS2 |
insulin receptor substrate 2 |
- PI3K Cascade
- IRS-mediated signalling
- SOS-mediated signalling
- SOS-mediated signalling
- PIP3 activates AKT signaling
- Interleukin-7 signaling
- PI3K/AKT activation
- PI3K/AKT activation
- Constitutive Signaling by Aberrant PI3K in Cancer
- IRS-related events triggered by IGF1R
- Signaling by Leptin
- RAF/MAP kinase cascade
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- IRS activation
- Signal attenuation
- RET signaling
- Signaling by Erythropoietin
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phospholipase C gamma (PLCG)
- Erythropoietin activates STAT5
- Erythropoietin activates RAS
- Erythropoietin activates RAS
- Growth hormone receptor signaling
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IRS4 |
insulin receptor substrate 4 |
- IRS-related events triggered by IGF1R
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ITIH1 |
inter-alpha-trypsin inhibitor heavy chain 1 |
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- Zinc
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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MRAS |
muscle RAS oncogene homolog |
- RAF activation
- Signaling by MRAS-complex mutants
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NEDD4L |
NEDD4 like E3 ubiquitin protein ligase |
- Budding and maturation of HIV virion
- Downregulation of TGF-beta receptor signaling
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Stimuli-sensing channels
- Antigen processing: Ubiquitination & Proteasome degradation
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NEDD9 |
neural precursor cell expressed, developmentally down-regulated 9 |
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PDK1 |
pyruvate dehydrogenase kinase 1 |
- Regulation of pyruvate dehydrogenase (PDH) complex
- Signaling by Retinoic Acid
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- 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE
- Dichloroacetic acid
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PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
- PI3K Cascade
- IRS-mediated signalling
- GPVI-mediated activation cascade
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- PI3K events in ERBB4 signaling
- PIP3 activates AKT signaling
- Interleukin-7 signaling
- Interleukin-7 signaling
- Signaling by SCF-KIT
- Synthesis of PIPs at the plasma membrane
- GAB1 signalosome
- Signaling by cytosolic FGFR1 fusion mutants
- Downstream signal transduction
- PI3K events in ERBB2 signaling
- PI3K/AKT activation
- Downstream TCR signaling
- Role of phospholipids in phagocytosis
- Tie2 Signaling
- Constitutive Signaling by Aberrant PI3K in Cancer
- DAP12 signaling
- Role of LAT2/NTAL/LAB on calcium mobilization
- Nephrin family interactions
- Costimulation by the CD28 family
- CD28 dependent PI3K/Akt signaling
- G alpha (q) signalling events
- GP1b-IX-V activation signalling
- VEGFA-VEGFR2 Pathway
- VEGFA-VEGFR2 Pathway
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- Constitutive Signaling by EGFRvIII
- PI-3K cascade:FGFR1
- PI-3K cascade:FGFR2
- PI-3K cascade:FGFR3
- PI-3K cascade:FGFR4
- Signaling by FGFR2 in disease
- Signaling by FGFR4 in disease
- Signaling by FGFR1 in disease
- RAF/MAP kinase cascade
- Interleukin-4 and Interleukin-13 signaling
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- MET activates PI3K/AKT signaling
- Signaling by FGFR3 fusions in cancer
- Signaling by FGFR3 point mutants in cancer
- RET signaling
- Extra-nuclear estrogen signaling
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Activated NTRK2 signals through PI3K
- Interleukin receptor SHC signaling
- Regulation of signaling by CBL
- Regulation of signaling by CBL
- Activated NTRK3 signals through PI3K
- FLT3 Signaling
- FLT3 Signaling
- Signaling by ERBB2 KD Mutants
- Signaling by ERBB2 ECD mutants
- Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
- Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
- Signaling by PDGFRA extracellular domain mutants
- Signaling by FLT3 fusion proteins
- Signaling by FLT3 fusion proteins
- Signaling by FLT3 ITD and TKD mutants
- Signaling by FLT3 ITD and TKD mutants
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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- Isoprenaline
- SF1126
- Enzastaurin
- Wortmannin
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PIK3R3 |
phosphoinositide-3-kinase regulatory subunit 3 |
- GPVI-mediated activation cascade
- PIP3 activates AKT signaling
- Interleukin-7 signaling
- Interleukin-7 signaling
- Signaling by SCF-KIT
- Synthesis of PIPs at the plasma membrane
- Constitutive Signaling by Aberrant PI3K in Cancer
- Costimulation by the CD28 family
- CD28 dependent PI3K/Akt signaling
- G alpha (q) signalling events
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- RET signaling
- Extra-nuclear estrogen signaling
- Interleukin receptor SHC signaling
- Regulation of signaling by CBL
- Regulation of signaling by CBL
- Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
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