|
|
CDH7 |
cadherin 7 |
- Adherens junctions interactions
|
|
|
|
|
CDH8 |
cadherin 8 |
- Adherens junctions interactions
|
|
|
|
|
CDH9 |
cadherin 9 |
- Adherens junctions interactions
|
|
|
|
|
CDON |
cell adhesion associated, oncogene regulated |
- Myogenesis
- Myogenesis
- Ligand-receptor interactions
- Activation of SMO
|
|
|
|
|
CEBPA |
CCAAT enhancer binding protein alpha |
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
|
|
- Acute myeloid leukemia (AML)
|
|
|
CHD8 |
chromodomain helicase DNA binding protein 8 |
- Deactivation of the beta-catenin transactivating complex
|
|
|
|
|
CSNK1D |
casein kinase 1 delta |
- COPII-mediated vesicle transport
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Circadian Clock
- Anchoring of the basal body to the plasma membrane
- Major pathway of rRNA processing in the nucleolus and cytosol
- AURKA Activation by TPX2
|
|
|
|
|
CTNNA1 |
catenin alpha 1 |
- Adherens junctions interactions
- VEGFR2 mediated vascular permeability
- Myogenesis
- Myogenesis
- RHO GTPases activate IQGAPs
|
|
|
|
|
CTNNA3 |
catenin alpha 3 |
|
|
|
|
|
CTNNBIP1 |
catenin beta interacting protein 1 |
- Deactivation of the beta-catenin transactivating complex
|
|
|
|
|
CTNND2 |
catenin delta 2 |
|
|
- Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
|
|
|
DLG5 |
discs large MAGUK scaffold protein 5 |
|
|
|
|
|
DSC3 |
desmocollin 3 |
- Keratinization
- Formation of the cornified envelope
|
|
- Hypotrichosis and recurrent skin vesicles
|
|
|
DVL1 |
dishevelled segment polarity protein 1 |
- TCF dependent signaling in response to WNT
- WNT mediated activation of DVL
- PCP/CE pathway
- PCP/CE pathway
- Degradation of DVL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Negative regulation of TCF-dependent signaling by DVL-interacting proteins
- RHO GTPases Activate Formins
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
|
|
|
|
|
DVL3 |
dishevelled segment polarity protein 3 |
- TCF dependent signaling in response to WNT
- WNT mediated activation of DVL
- PCP/CE pathway
- PCP/CE pathway
- Degradation of DVL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Negative regulation of TCF-dependent signaling by DVL-interacting proteins
- RHO GTPases Activate Formins
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
|
|
|
|
|
ELAVL1 |
ELAV like RNA binding protein 1 |
- HuR (ELAVL1) binds and stabilizes mRNA
- mRNA Splicing - Major Pathway
|
|
|
|
|
EP300 |
E1A binding protein p300 |
- Regulation of gene expression by Hypoxia-inducible Factor
- RORA activates gene expression
- Polo-like kinase mediated events
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- PPARA activates gene expression
- PPARA activates gene expression
- Formation of the beta-catenin:TCF transactivating complex
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH2 intracellular domain regulates transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
- HATs acetylate histones
- Attenuation phase
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- SUMOylation of transcription cofactors
- Circadian Clock
- B-WICH complex positively regulates rRNA expression
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- CD209 (DC-SIGN) signaling
- Metalloprotease DUBs
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Regulation of TP53 Activity through Acetylation
- Regulation of TP53 Activity through Methylation
- PI5P Regulates TP53 Acetylation
- Activation of the TFAP2 (AP-2) family of transcription factors
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- RUNX3 regulates NOTCH signaling
- RUNX3 regulates NOTCH signaling
- Regulation of RUNX3 expression and activity
- RUNX3 regulates p14-ARF
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH4 Intracellular Domain Regulates Transcription
- Estrogen-dependent gene expression
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- NGF-stimulated transcription
- NGF-stimulated transcription
- TRAF3-dependent IRF activation pathway
- TRAF6 mediated IRF7 activation
- FOXO-mediated transcription of cell death genes
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- Regulation of FOXO transcriptional activity by acetylation
- Regulation of FOXO transcriptional activity by acetylation
|
|
- Rubinstein-Taybi syndrome
|
|
|
ERBIN |
erbb2 interacting protein |
- Signaling by ERBB2
- Downregulation of ERBB2 signaling
- Constitutive Signaling by Overexpressed ERBB2
- Drug-mediated inhibition of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Resistance of ERBB2 KD mutants to trastuzumab
- Resistance of ERBB2 KD mutants to sapitinib
- Resistance of ERBB2 KD mutants to tesevatinib
- Resistance of ERBB2 KD mutants to neratinib
- Resistance of ERBB2 KD mutants to osimertinib
- Resistance of ERBB2 KD mutants to afatinib
- Resistance of ERBB2 KD mutants to AEE788
- Resistance of ERBB2 KD mutants to lapatinib
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Drug resistance in ERBB2 TMD/JMD mutants
|
|
|
|
|
EZR |
ezrin |
- Netrin-1 signaling
- Recycling pathway of L1
- Recycling pathway of L1
|
|
|
|
|
FBXW2 |
F-box and WD repeat domain containing 2 |
- Association of TriC/CCT with target proteins during biosynthesis
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|