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NPM1 |
nucleophosmin 1 |
- Nuclear import of Rev protein
- Nuclear import of Rev protein
- SUMOylation of transcription cofactors
- Deposition of new CENPA-containing nucleosomes at the centromere
- TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
- TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
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PSMC3 |
proteasome 26S subunit, ATPase 3 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- Neutrophil degranulation
- CDT1 association with the CDC6:ORC:origin complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
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RUVBL2 |
RuvB like AAA ATPase 2 |
- Telomere Extension By Telomerase
- HATs acetylate histones
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SNRPA |
small nuclear ribonucleoprotein polypeptide A |
- mRNA Splicing - Major Pathway
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VAMP1 |
vesicle associated membrane protein 1 |
- Toxicity of botulinum toxin type D (botD)
- Toxicity of botulinum toxin type F (botF)
- Toxicity of botulinum toxin type G (botG)
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sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene |
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ACTN4 |
actinin alpha 4 |
- Platelet degranulation
- Nephrin family interactions
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- Nephrotic syndrome and focal segmental glomerulosclerosis
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AHNAK |
AHNAK nucleoprotein |
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ANAPC15 |
anaphase promoting complex subunit 15 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
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ANGPTL4 |
angiopoietin like 4 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Assembly of active LPL and LIPC lipase complexes
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ANKRA2 |
ankyrin repeat family A member 2 |
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ANKRD12 |
ankyrin repeat domain 12 |
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AOPEP |
aminopeptidase O (putative) |
- Metabolism of Angiotensinogen to Angiotensins
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ARFIP2 |
ADP ribosylation factor interacting protein 2 |
- Retrograde transport at the Trans-Golgi-Network
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ARNT |
aryl hydrocarbon receptor nuclear translocator |
- Regulation of gene expression by Hypoxia-inducible Factor
- PPARA activates gene expression
- Phase I - Functionalization of compounds
- Endogenous sterols
- Xenobiotics
- Aryl hydrocarbon receptor signalling
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ASPRV1 |
aspartic peptidase retroviral like 1 |
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AZIN1 |
antizyme inhibitor 1 |
- Regulation of ornithine decarboxylase (ODC)
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CARF |
calcium responsive transcription factor |
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CASC3 |
CASC3 exon junction complex subunit |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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CCDC180 |
coiled-coil domain containing 180 |
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