JOSD1 and KRT86

Data Source:
BioGRID (two hybrid)

		JOSD1	KRT86
Description		Josephin domain containing 1	keratin 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane	Extracellular Space Cytosol Keratin Filament
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Protein Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation	Keratinization Cornification
Pathways		Josephin domain DUBs	Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Plateletcrit ( 32888494) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		38 interacting genes: ADAMTSL4 CARD10 CYSRT1 FBLN2 KRT27 KRT31 KRT34 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-2 KRTAP9-3 LNX1 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA PJA1 STUB1 TGM1 TRAF1 TRIM23 TRIM27 TRIM54 TRIM63 UBC USP15 USP21 USP28	45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655
Entrez ID		9929	3892
HPRD ID		08823	03567
Ensembl ID		ENSG00000100221	ENSG00000170442
Uniprot IDs		A0A024R1P5 Q15040	A8K872 O43790
PDB IDs
Enriched GO Terms of Interacting Partners?
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