JOSD1 and FBLN2

Data Source:
BioGRID (two hybrid)

		JOSD1	FBLN2
Description		Josephin domain containing 1	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Josephin domain DUBs	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Plateletcrit ( 32888494) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		38 interacting genes: ADAMTSL4 CARD10 CYSRT1 FBLN2 KRT27 KRT31 KRT34 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-2 KRTAP9-3 LNX1 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA PJA1 STUB1 TGM1 TRAF1 TRIM23 TRIM27 TRIM54 TRIM63 UBC USP15 USP21 USP28	30 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D NID1 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		9929	2199
HPRD ID		08823	00630
Ensembl ID		ENSG00000100221	ENSG00000163520
Uniprot IDs		A0A024R1P5 Q15040	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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