RUSC2 and DLST

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RUSC2	DLST
Description		RUN and SH3 domain containing 2	dihydrolipoamide S-succinyltransferase
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Exosome	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Centriolar Satellite Oxoglutarate Dehydrogenase Complex
	Molecular Function	Protein Binding Small GTPase Binding	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Biological_process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process Protein Phosphopantetheinylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation
Pathways			Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Psoriasis ( 25903422)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Eosinophil counts ( 32888494) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)
Interacting Genes		9 interacting genes: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPRA	16 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UBE2D2 UMPS ZBTB16 ZHX1
Entrez ID		9853	1743
HPRD ID		18009	00520
Ensembl ID		ENSG00000198853	ENSG00000119689
Uniprot IDs		Q8N2Y8	A0A024R6C9 B7Z6J1 P36957
PDB IDs		6IF2	6H05
Enriched GO Terms of Interacting Partners?
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