DLST and CCDC86

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	CCDC86
Description		dihydrolipoamide S-succinyltransferase	coiled-coil domain containing 86
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Centriolar Satellite Oxoglutarate Dehydrogenase Complex	Nucleoplasm Chromosome Nucleolus
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups	RNA Binding Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process Protein Phosphopantetheinylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation	Viral Process
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Eosinophil counts ( 32888494) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)	Wegener's granulomatosis ( 23740775)
Interacting Genes		16 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UBE2D2 UMPS ZBTB16 ZHX1	2 interacting genes: DLST SRPK2
Entrez ID		1743	79080
HPRD ID		00520	08322
Ensembl ID		ENSG00000119689	ENSG00000110104
Uniprot IDs		A0A024R6C9 B7Z6J1 P36957	Q9H6F5
PDB IDs		6H05
Enriched GO Terms of Interacting Partners?
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