TRIM14 and ZGPAT

Data Source:
BioGRID (two hybrid)

		TRIM14	ZGPAT
Description		tripartite motif containing 14	zinc finger CCCH-type and G-patch domain containing
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Cytosol Phagocytic Vesicle	Chromatin Nucleus Nucleoplasm Plasma Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) High density lipoprotein cholesterol levels ( 31928498) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1) ( 28166213) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Prostate cancer ( 31562322 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633) Waist circumference ( 31928498)
Interacting Genes		84 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	77 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 C1D CARD9 CAVIN4 CCDC13 CCDC196 CCDC33 CCDC57 CCHCR1 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CNKSR1 CTNNA1 DHX15 DVL2 DYDC1 EP400 FAM9B GATAD2B GOLGA2 GOLGA6L9 HOOK2 HSF2BP IHO1 IKZF3 KIAA1328 KIFC3 KRT15 KRT31 KRT40 LCA5L LDOC1 LNX1 LZTS1 LZTS2 MID2 MIPOL1 NEBL PHC2 PPP1R13B PRPF3 S100A10 SCNM1 SERTAD3 SNRPA1 SPAG5 SSX2IP STAC3 TADA2B TFIP11 THAP1 THAP6 TLE5 TP53BP2 TRIM14 TRIM27 TRIM54 UBXN11 UPF2 ZBTB8A ZC2HC1B ZNF177 ZNF24 ZNF329 ZNF426 ZNF559-ZNF177 ZNF587 ZNF688 ZNF71 ZSCAN22 ZXDB
Entrez ID		9830	84619
HPRD ID		05948	15736
Ensembl ID		ENSG00000106785	ENSG00000197114
Uniprot IDs		A0A024R165 Q14142	A0A0S2Z5X3 Q8N5A5
PDB IDs		6JBM	4II1
Enriched GO Terms of Interacting Partners?
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