ZSCAN12 and CENPH

Data Source:
BioGRID (two hybrid)

		ZSCAN12	CENPH
Description		zinc finger and SCAN domain containing 12	centromere protein H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Kinetochore Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Lung cancer ( 28604730) Refractive error ( 32231278) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sleep duration (short sleep) ( 30846698) Smoking initiation (ever regular vs never regular) ( 30679032) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: BICD2 CENPH CEP70 FAM161A KRTAP10-1 KRTAP10-8 LMNA MID2 MTUS2 PGBD1 RACK1 SCAND1 SRPK2 SSX2IP TFIP11 VCX VLDLR VPS26A ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF473 ZNF496 ZSCAN21 ZSCAN32	19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12
Entrez ID		9753	64946
HPRD ID		15767	12029
Ensembl ID		ENSG00000158691	ENSG00000153044
Uniprot IDs			A0A0S2Z5T0 Q9H3R5
PDB IDs
Enriched GO Terms of Interacting Partners?
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