CENPH and KIF2C

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CENPH	KIF2C
Description		centromere protein H	kinesin family member 2C
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end
	Molecular Function	Protein Binding Kinetochore Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Centromeric DNA Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS
Interacting Genes		19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CENPK DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12	10 interacting genes: APP AURKA CENPH CSNK2B H3-4 NDEL1 PLK1 SUMO2 VHL ZNF566
Entrez ID		64946	11004
HPRD ID		12029	05172
Ensembl ID		ENSG00000153044	ENSG00000142945
Uniprot IDs		A0A0S2Z5T0 Q9H3R5	A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661
PDB IDs			2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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