CD69 and CLDN1

Data Source:
BioGRID (two hybrid)

		CD69	CLDN1
Description		CD69 molecule	claudin 1
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane External Side Of Plasma Membrane Protein-containing Complex	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Protein-containing Complex Tight Junction
	Molecular Function	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding Identical Protein Binding	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process		Cell Adhesion Aging Establishment Of Blood-nerve Barrier Response To Toxic Substance Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Cell Migration Response To Lipopolysaccharide Cell Junction Maintenance Maintenance Of Blood-brain Barrier Hyperosmotic Salinity Response Cell-cell Junction Organization Response To Ethanol Viral Entry Into Host Cell Protein Complex Oligomerization Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Establishment Of Skin Barrier Xenobiotic Transport Across Blood-nerve Barrier Response To Interleukin-18 Bicellular Tight Junction Assembly Cellular Response To Lead Ion Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Response To Dexamethasone Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Wound Healing Establishment Of Endothelial Intestinal Barrier Liver Regeneration Positive Regulation Of Bicellular Tight Junction Assembly Cellular Response To Butyrate
Pathways			Tight junction interactions
Drugs
Diseases			Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome; Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC)
GWAS		Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 32888494 27863252) Type 1 diabetes ( 25751624 19430480) White blood cell count ( 32888494)	Optic disc size ( 31809533) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes		14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B	18 interacting genes: BRD4 CD69 CD79A CLDN3 DRG1 FNDC9 LNX1 MMP14 MMP2 MPDZ MS4A3 PATJ TJP1 TJP2 TJP3 TMEM179B TMEM9 WNK4
Entrez ID		969	9076
HPRD ID		00119	04760
Ensembl ID		ENSG00000110848	ENSG00000163347
Uniprot IDs		Q07108 Q53ZX0	A5JSJ9 O95832
PDB IDs		1E87 1E8I 1FM5 3CCK 3HUP
Enriched GO Terms of Interacting Partners?
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