GOSR2 and MFSD14B

Data Source:
BioGRID (two hybrid)

		GOSR2	MFSD14B
Description		golgi SNAP receptor complex member 2	major facilitator superfamily domain containing 14B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Protein Targeting To Vacuole Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport IRE1-mediated Unfolded Protein Response Retrograde Transport, Endosome To Golgi COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus	Transmembrane Transport
Pathways		COPII-mediated vesicle transport XBP1(S) activates chaperone genes Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic
Drugs
Diseases
GWAS		Aortic root size ( 28394258) Atrial fibrillation ( 29892015) Blood pressure ( 21909110) Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 26426971) Cleft lip with or without cleft palate ( 28054174) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Feeling guilty ( 29500382) Feeling worry ( 29500382) Hemoglobin levels ( 32327693) Idiopathic pulmonary fibrosis ( 29066090) Ischemic stroke ( 29930801) Mean arterial pressure ( 27618448) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Myocardial infarction ( 30226566) Nonsyndromic cleft lip with cleft palate ( 28232668) Orofacial clefts ( 28054174) Pulse pressure ( 27841878 28739976 30578418) QRS duration ( 27577874 30012220 21076409) QT interval ( 29874175) Systolic blood pressure ( 28135244 27841878 21909115 28739976 27618447 27618452 30578418)
Interacting Genes		51 interacting genes: APP AQP6 ARF1 ARL13B BET1 BLCAP CREB3L1 CYB561 CYBRD1 EBP ELOVL4 ELOVL5 FAM174A FAM209A FATE1 GOLGA8EP GOLGA8F GPR152 GPR42 GPX8 HIBADH HSD17B13 IER3IP1 JAGN1 KASH5 LEUTX LIME1 LMNA MARCHF8 MFF MFSD14B MFSD5 NAPA PELI1 RETREG3 RIC3 RNF19B SLC10A1 SLC10A6 SPAG4 STX1A STX4 STX5 TLCD4 TM4SF19 TMCO5A TMEM106A TMEM106C TMEM205 TMEM35A USO1	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		9570	84641
HPRD ID		04937	07869
Ensembl ID		ENSG00000108433	ENSG00000148110
Uniprot IDs		A0A1W2PQE0 A0A1W2PQM3 A0A1W2PR02 A0A1W2PRL0 I3NI02 O14653	Q5SR56
PDB IDs		3EG9
Enriched GO Terms of Interacting Partners?
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