CIR1 and SLC25A17

Data Source:
BioGRID (genetic interference)

		CIR1	SLC25A17
Description		corepressor interacting with RBPJ, CIR1	solute carrier family 25 member 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Nuclear Speck Protein-containing Complex	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Kinase Binding Histone Deacetylase Binding Protein-containing Complex Binding	Adenine Nucleotide Transmembrane Transporter Activity ATP Transmembrane Transporter Activity Protein Binding ADP Transmembrane Transporter Activity Coenzyme A Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FMN Transmembrane Transporter Activity Chaperone Binding NAD Transmembrane Transporter Activity AMP Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated	Fatty Acid Alpha-oxidation Fatty Acid Beta-oxidation ADP Transport ATP Transport Fatty Acid Transport Coenzyme A Transmembrane Transport FAD Transmembrane Transport NAD Transmembrane Transport AMP Transport
Pathways			Alpha-oxidation of phytanate Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525) Adult body size ( 32376654) Chronotype ( 30696823) Hand grip strength ( 29691431) Triglyceride levels ( 32203549)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Coffee consumption ( 31046077) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Feeling nervous ( 29500382) Irritable mood ( 29500382) Low density lipoprotein cholesterol levels ( 29083408) Neurociticism ( 29500382) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: CCDC33 CEP76 DPPA4 HDAC2 MB21D2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1	2 interacting genes: MEOX2 PEX19
Entrez ID		9541	10478
HPRD ID		05568	08425
Ensembl ID		ENSG00000138433	ENSG00000100372
Uniprot IDs		Q86X95	B4DP73 B4DU97 F6RTR7 O43808
PDB IDs		6ZYM
Enriched GO Terms of Interacting Partners?
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