AKAP5 and ROPN1L

Data Source:
BioGRID (two hybrid)

		AKAP5	ROPN1L
Description		A-kinase anchoring protein 5	rhophilin associated tail protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Dendrite Membrane Dendritic Spine Membrane Raft Excitatory Synapse Postsynaptic Recycling Endosome	Extracellular Region Cytoplasm Cilium Motile Cilium
	Molecular Function	Protein Binding Calmodulin Binding Adenylate Cyclase Binding SH3 Domain Binding Protein Phosphatase 2B Binding Beta-2 Adrenergic Receptor Binding Protein Kinase A Regulatory Subunit Binding Glutamate Receptor Binding GABA Receptor Binding Protein Kinase A Binding Molecular Adaptor Activity Scaffold Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Chemical Synaptic Transmission Regulation Of Protein Kinase A Signaling Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endosome To Plasma Membrane Protein Transport	Regulation Of Protein Phosphorylation Epithelial Cilium Movement Involved In Extracellular Fluid Movement Flagellated Sperm Motility Sperm Capacitation
Pathways		Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Trafficking of AMPA receptors ROBO receptors bind AKAP5 ROBO receptors bind AKAP5
Drugs
Diseases
GWAS			Body mass index ( 22446040) Breast cancer ( 21424380) Coronary artery disease in type 1 diabetes ( 29695241) Dermatomyositis or juvenile dermatomyositis ( 26362759) Mean arterial pressure ( 27618448) Triglyceride levels ( 31170924)
Interacting Genes		21 interacting genes: ADRB2 CALM1 DLG1 DLG4 FOS GABRB1 GABRB3 IQGAP1 JUN KCNJ2 MDM2 PPP3CA PRKAR1A PRKAR2A PRKAR2B PRKCA RET ROPN1 ROPN1L TP53 TRPV1	8 interacting genes: AKAP14 AKAP3 AKAP5 AKAP7 APP BEX2 RSPH3 SPA17
Entrez ID		9495	83853
HPRD ID		05255	17986
Ensembl ID		ENSG00000179841	ENSG00000145491
Uniprot IDs		P24588 Q6PG46	Q96C74
PDB IDs		2H9R 3LL8 5NIN
Enriched GO Terms of Interacting Partners?
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