AKAP6 and PDE4D

  • Data Source:
  • HPRD (in vivo, in vitro)

AKAP6

PDE4D

Description A-kinase anchoring protein 6 phosphodiesterase 4D
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065)
  • Amygdala volume ( 31530798)
  • Asthma ( 19426955)
  • Brain morphology (MOSTest) ( 32665545)
  • Breast cancer ( 29059683 23535729)
  • Chronotype ( 30696823)
  • Cognitive function ( 28808816)
  • Cortical surface area (MOSTest) ( 32665545)
  • Esophageal cancer ( 21642993)
  • Esophageal squamous cell carcinoma ( 25129146)
  • Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521)
  • General cognitive ability ( 29844566)
  • HDL cholesterol levels ( 32203549)
  • Immune response to smallpox vaccine (IL-6) ( 22610502)
  • Intelligence (MTAG) ( 29326435)
  • Mitochondrial DNA levels ( 30326835)
  • Neuroticism ( 17667963)
  • Obesity-related traits ( 23251661)
  • Obsessive-compulsive disorder ( 30456828)
  • Plasma parathyroid hormone levels ( 30134803)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Response to antipsychotic treatment ( 23241943)
  • Sleep duration (long sleep) ( 30846698)
  • Sleep-related phenotypes ( 17903308)
  • Subcortical volume (MOSTest) ( 32665545)
  • Thyroid stimulating hormone levels ( 32769997)
Interacting Genes 9 interacting genes: CALM1 CDC5L DISC1 DTNBP1 PDE4D PPP2CA PRKAR2A RYR1 RYR2 28 interacting genes: ABL1 AKAP6 APP ARRB1 ARRB2 COIL CSNK1A1 FBXO7 FYN GOLGA8EP GOLGA8F GRB2 GSK3B HRAS LYN MAGEA6 MAPK1 MDM2 PAFAH1B1 PDE4DIP PIAS4 PIK3R1 PRKACA RACK1 SPTAN1 SRC TRAF1 TRIM23
Entrez ID 9472 5144
HPRD ID 05257 02530
Ensembl ID ENSG00000151320 ENSG00000113448
Uniprot IDs B2RP22 Q13023 A0A140VJR0 Q08499
PDB IDs 1E9K 1MKD 1OYN 1PTW 1Q9M 1TB7 1TBB 1XOM 1XON 1XOQ 1XOR 1Y2B 1Y2C 1Y2D 1Y2E 1Y2K 1ZKN 2FM0 2FM5 2PW3 2QYN 3G4G 3G4I 3G4K 3G4L 3G58 3IAD 3IAK 3K4S 3SL3 3SL4 3SL5 3SL6 3SL8 3V9B 4OGB 4W1O 4WCU 5K1I 5K32 5LBO 5TKB 5WH5 5WH6 5WQA 6AKR 6BOJ 6F6U 6F8R 6F8T 6F8U 6F8V 6F8W 6F8X 6FDC 6FDI 6FE7 6FEB 6FET 6FT0 6FTA 6FTW 6FW3 6HWO 6IAG 6IBF 6IM6 6IMB 6IMD 6IMI 6IMO 6IMR 6IMT 6IND 6INK 6INM 6KJZ 6KK0 6NJH 6NJI 6NJJ 6RCW 6ZBA
Enriched GO Terms of Interacting Partners?
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