TRIP10 and ARHGAP17

Data Source:
BioGRID (two hybrid, two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		TRIP10	ARHGAP17
Description		thyroid hormone receptor interactor 10	Rho GTPase activating protein 17
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Intracellular Anatomical Structure Nucleoplasm Cytosol Plasma Membrane Bicellular Tight Junction
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding
	Biological Process	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization	Actin Filament Organization Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Clathrin-mediated endocytosis	Rho GTPase cycle
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		41 interacting genes: ABI1 ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 DTX3 HOXC11 HTT JRK LYN MEOX1 MEOX2 NKX2-5 PAX6 PDE6G POT1 PRKACA RHOJ RHOQ RIN1 RXRA SF3A2 SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THAP1 THRB TINF2 UTF1 WAS WASF1 WASL WBP11 ZBTB7B	16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10
Entrez ID		9322	55114
HPRD ID		05142	12207
Ensembl ID		ENSG00000125733	ENSG00000140750
Uniprot IDs		Q15642 W4VSQ9	Q68EM7
PDB IDs		2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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