ARHGAP17 and SH3GLB1

Data Source:
HPRD (in vitro)

		ARHGAP17	SH3GLB1
Description		Rho GTPase activating protein 17	SH3 domain containing GRB2 like, endophilin B1
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Cytosol Plasma Membrane Bicellular Tight Junction	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Actin Filament Organization Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576
Entrez ID		55114	51100
HPRD ID		12207	15333
Ensembl ID		ENSG00000140750	ENSG00000097033
Uniprot IDs		Q68EM7	A0A087WW40 A0A140VJU5 Q9Y371
PDB IDs			6UP6 6UPN
Enriched GO Terms of Interacting Partners?
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