RCSD1 and MAPK12

Data Source:
BioGRID (enzymatic study)

		RCSD1	MAPK12
Description		RCSD domain containing 1	mitogen-activated protein kinase 12
Image		No pdb structure
GO Annotations	Cellular Component	Actin Filament	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Actin Filament Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding
	Biological Process	Skeletal Muscle Contraction Cellular Hyperosmotic Response	MAPK Cascade DNA Damage Induced Protein Phosphorylation Cell Cycle Arrest Signal Transduction Muscle Organ Development Positive Regulation Of Peptidase Activity Peptidyl-serine Phosphorylation Intracellular Signal Transduction Myoblast Differentiation Positive Regulation Of Muscle Cell Differentiation
Pathways			NOD1/2 Signaling Pathway p38MAPK events Activation of PPARGC1A (PGC-1alpha) by phosphorylation DSCAM interactions VEGFA-VEGFR2 Pathway Myogenesis Myogenesis Negative regulation of MAPK pathway
Drugs			Minocycline Phosphonothreonine Phosphoaminophosphonic Acid-Adenylate Ester KC706 CEP-1347
Diseases
GWAS		Asthma ( 31959851) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Acne (severe) ( 24927181) Diverticular disease ( 30177863) Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes		3 interacting genes: MAPK12 MAPKAPK2 MAPKAPK3	29 interacting genes: DLG1 DLG2 DLG3 DLG4 DUSP1 EEF2K ERBIN GRB2 GTF2I HTRA2 MAP2K3 MAP2K4 MAP2K6 MAPKAPK5 MAPT MBP PATJ PDGFRL PKN1 PTPN3 PTPN4 RCSD1 RGS3 SH3BP5 SIAH1 SNTA1 SNTB1 SRPK1 TERF1
Entrez ID		92241	6300
HPRD ID		10077	03868
Ensembl ID		ENSG00000198771	ENSG00000188130
Uniprot IDs		B7ZKW8 Q6JBY9	P53778 Q6N076
PDB IDs			1CM8 4QUM 6UNA
Enriched GO Terms of Interacting Partners?
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