ZW10 and ZWILCH

Data Source:
HPRD (in vivo, in vitro)

		ZW10	ZWILCH
Description		zw10 kinetochore protein	zwilch kinetochore protein
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex	Kinetochore Condensed Chromosome Kinetochore Cytosol RZZ Complex
	Molecular Function	Protein Binding Centromeric DNA Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Mitotic Metaphase Plate Congression Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly Signal Transduction Involved In Mitotic Cell Cycle Checkpoint	Protein Localization To Kinetochore Cell Division Signal Transduction Involved In Mitotic Cell Cycle Checkpoint
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Parental longevity (father's attained age) ( 29227965)	Body mass index ( 29273807)
Interacting Genes		7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT	2 interacting genes: KNTC1 ZW10
Entrez ID		9183	55055
HPRD ID		04902	07640
Ensembl ID		ENSG00000086827	ENSG00000174442
Uniprot IDs		O43264	A8K4T3 Q9H900
PDB IDs			3IF8
Enriched GO Terms of Interacting Partners?
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