ATP23 and FOXH1

Data Source:
BioGRID (two hybrid)

		ATP23	FOXH1
Description		ATP23 metallopeptidase and ATP synthase assembly factor homolog	forkhead box H1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane DNA-dependent Protein Kinase-DNA Ligase 4 Complex Cell Junction Extrinsic Component Of Mitochondrial Inner Membrane Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Activin Responsive Factor Complex
	Molecular Function	Metalloendopeptidase Activity DNA-dependent Protein Kinase Activity Protein Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding SMAD Binding Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Protein Phosphorylation Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Protein Processing	Negative Regulation Of Transcription By RNA Polymerase II Heart Looping Secondary Heart Field Specification Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Pathways			Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS			Blood metabolite levels ( 26401656) Educational attainment ( 25201988) General cognitive ability ( 29844566)
Interacting Genes		31 interacting genes: ABI2 ACTN3 AP2B1 ATG5 BAG4 BCL6 C1orf109 CCDC120 CSTF2 CSTF2T CTNNA3 DUSP21 EXOC8 FOXH1 FOXI1 FRS3 GLYCTK GUCD1 HNRNPF HOXA1 HR KLC3 KRTAP10-1 MGAT5B PLSCR4 PPP1R16A STK16 TRIP6 TSSK3 XRCC6 ZIC1	67 interacting genes: AOC1 ARID5A ATP23 ATXN1L BATF2 C10orf55 C11orf1 C19orf54 CEACAM6 CRX CRYBA1 CYSRT1 DAZAP2 DRAP1 FAM168B FAM83A FOXD2 FOXG1 HDHD3 HEY1 HLX HOXA1 HSF4 KLHL26 KRTAP11-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP7-1 LASP1 MAGED1 MGAT5B MSX2 NKX2-5 NOTO OXER1 PLA2G10 PNMA5 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM46 RBPMS2 RNF144B SERGEF SMAD2 SMAD3 SMAD4 SOX14 SOX4 TEKT5 TFG TLX3 TSC1 UBAP2 UFSP1 ZC3H10 ZIC1 ZNF34 ZNF503
Entrez ID		91419	8928
HPRD ID		17256	04689
Ensembl ID		ENSG00000166896	ENSG00000160973
Uniprot IDs		Q9Y6H3	O75593
PDB IDs			5XOC
Enriched GO Terms of Interacting Partners?
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