ATP23 and FOXI1

Data Source:
BioGRID (two hybrid)

		ATP23	FOXI1
Description		ATP23 metallopeptidase and ATP synthase assembly factor homolog	forkhead box I1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane DNA-dependent Protein Kinase-DNA Ligase 4 Complex Cell Junction Extrinsic Component Of Mitochondrial Inner Membrane Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	Metalloendopeptidase Activity DNA-dependent Protein Kinase Activity Protein Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Protein Phosphorylation Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Protein Processing	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases			Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS			Acne (severe) ( 24927181) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
Interacting Genes		31 interacting genes: ABI2 ACTN3 AP2B1 ATG5 BAG4 BCL6 C1orf109 CCDC120 CSTF2 CSTF2T CTNNA3 DUSP21 EXOC8 FOXH1 FOXI1 FRS3 GLYCTK GUCD1 HNRNPF HOXA1 HR KLC3 KRTAP10-1 MGAT5B PLSCR4 PPP1R16A STK16 TRIP6 TSSK3 XRCC6 ZIC1	26 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX
Entrez ID		91419	2299
HPRD ID		17256	03057
Ensembl ID		ENSG00000166896	ENSG00000168269
Uniprot IDs		Q9Y6H3	E0XEN6 Q12951
PDB IDs
Enriched GO Terms of Interacting Partners?
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