FOXI1 and ARSA

Data Source:
BioGRID (two hybrid)

		FOXI1	ARSA
Description		forkhead box I1	arylsulfatase A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleolus Intracellular Membrane-bounded Organelle	Extracellular Region Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II	Glycosphingolipid Metabolic Process Neutrophil Degranulation
Pathways			Glycosphingolipid metabolism The activation of arylsulfatases Neutrophil degranulation
Drugs			4-Nitrocatechol sulfate 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter	Metachromatic leukodystrophy (MLD)
GWAS		Acne (severe) ( 24927181) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)	Blood metabolite levels ( 24816252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) QT interval (ambient particulate matter interaction) ( 28749367) Urinary metabolite levels in chronic kidney disease ( 31959995) vWF and FVIII levels ( 30586737)
Interacting Genes		26 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX	18 interacting genes: ANXA11 BMPR2 CAMK2B CCDC22 CETN2 CLEC4G CTSL EID2B FOXI1 GAL3ST1 PKN1 POU1F1 PPIC PROP1 RHOXF2 SNCA TRIP13 VENTX
Entrez ID		2299	410
HPRD ID		03057	09617
Ensembl ID		ENSG00000168269	ENSG00000100299
Uniprot IDs		E0XEN6 Q12951	A0A0C4DFZ2 B4DVI5 P15289
PDB IDs			1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8
Enriched GO Terms of Interacting Partners?
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