TAF1C and TAF1A

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TAF1C	TAF1A
Description		TATA-box binding protein associated factor, RNA polymerase I subunit C	TATA-box binding protein associated factor, RNA polymerase I subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity Protein Binding	DNA Binding Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Autism ( 22843504) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Visceral adipose tissue adjusted for BMI ( 22589738)	Trunk fat mass ( 28552196)
Interacting Genes		13 interacting genes: H2AX POLR1E RRN3 SMN1 TAF1A TAF1B TBP TK1 TP53 TRIM24 TTR UBTF UFD1	20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		9013	9015
HPRD ID		05364	05362
Ensembl ID		ENSG00000103168	ENSG00000143498
Uniprot IDs		B3KUE8 Q15572	A8K4K5 B4DS21 Q15573
PDB IDs
Enriched GO Terms of Interacting Partners?
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