WASF1 and CCDC196

Data Source:
BioGRID (two hybrid)

		WASF1	CCDC196
Description		WASP family member 1	coiled-coil domain containing 196
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytoskeleton Focal Adhesion Actin Cytoskeleton Lamellipodium SCAR Complex Dendrite Cytoplasm Protein-containing Complex Postsynapse
	Molecular Function	Actin Binding Protein Binding Small GTPase Binding Protein Kinase A Regulatory Subunit Binding Protein Kinase A Binding Arp2/3 Complex Binding
	Biological Process	Receptor-mediated Endocytosis Rac Protein Signal Transduction Actin Cytoskeleton Organization Actin Filament Polymerization Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein-containing Complex Assembly Mitochondrion Morphogenesis Lamellipodium Morphogenesis Dendrite Extension Modification Of Postsynaptic Actin Cytoskeleton Dendritic Transport Of Mitochondrion Cellular Response To Brain-derived Neurotrophic Factor Stimulus Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: ABI1 ABI3 ABL1 ACTB ACTG1 ACTR2 ACTR3 BAD BAIAP2 BRK1 CCDC196 CDC42 CDK5 CRK CXCL8 CYFIP2 DNMBP EFHC1 FYN GNAI1 GRB2 HSF2BP IFT20 IL12A ING5 LMO2 MAPKAPK2 NCK1 NCK2 NCKAP1 NYAP2 OSTF1 PFN1 PRKAR2A PSTPIP1 RAC1 SORBS2 SRGAP3 TRAF2 TRIP10	32 interacting genes: AMOTL2 ANKRD11 BORCS5 DTNB EIF3F HGS IFT74 KRT20 KRT28 KRT31 KRT34 KRT35 KRT37 KRT39 MEIS2 MEOX2 NXF1 PIK3R3 PKNOX2 RAB3IP SKA1 SNAPC5 STX11 SYCE1L SYCE2 TFIP11 TXLNA TXLNB UBL5 USHBP1 WASF1 ZGPAT
Entrez ID		8936	440184
HPRD ID		05434	14708
Ensembl ID		ENSG00000112290	ENSG00000196553
Uniprot IDs		Q92558
PDB IDs		3P8C 4N78
Enriched GO Terms of Interacting Partners?
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