PABPC4 and VPS26B

Data Source:
BioGRID (biochemical)

		PABPC4	VPS26B
Description		poly(A) binding protein cytoplasmic 4	VPS26, retromer complex component B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex	Endosome Early Endosome Late Endosome Cytosol Retromer Complex Retromer, Cargo-selective Complex Phagocytic Vesicle
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding Poly(C) RNA Binding	Protein Binding
	Biological Process	RNA Processing RNA Catabolic Process Translation Blood Coagulation Regulation Of MRNA Stability Myeloid Cell Development	Intracellular Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Cellular Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399 21300955) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronic obstructive pulmonary disease ( 30804561) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Coffee consumption ( 31046077) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27618448) HDL cholesterol ( 24097068 30275531 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) High density lipoprotein cholesterol levels ( 29615537) Mean arterial pressure ( 27618448) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552) Red cell distribution width ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Verbal declarative memory ( 25648963)
Interacting Genes		15 interacting genes: CDC42 DUX4 EEF1A1 GDF9 HAP1 IL7R MED31 PHLDA1 RIF1 SETDB1 SMAD9 SREK1 SRPK2 UBC XRN1	2 interacting genes: NPLOC4 VPS35
Entrez ID		8761	112936
HPRD ID		04557	14395
Ensembl ID		ENSG00000090621	ENSG00000151502
Uniprot IDs		Q13310	A0A024R3L9 Q4G0F5
PDB IDs
Enriched GO Terms of Interacting Partners?
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