VPS26B and NPLOC4

Data Source:
BioGRID (two hybrid)

		VPS26B	NPLOC4
Description		VPS26, retromer complex component B	NPL4 homolog, ubiquitin recognition factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Cytosol Retromer Complex Retromer, Cargo-selective Complex Phagocytic Vesicle	Nucleus Nucleoplasm Endoplasmic Reticulum Cytosol VCP-NPL4-UFD1 AAA ATPase Complex UFD1-NPL4 Complex Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Cellular Response To Interferon-gamma	Ubiquitin-dependent Protein Catabolic Process Golgi Organization Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Type I Interferon Production Negative Regulation Of RIG-I Signaling Pathway Error-free Translesion Synthesis
Pathways			Translesion Synthesis by POLH
Drugs
Diseases
GWAS		Verbal declarative memory ( 25648963)	Advanced age-related macular degeneration ( 26691988) Cataracts (operation) ( 31816047) Central corneal thickness ( 32528159) Eye color traits ( 20463881) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myopia ( 27182965) Non-albumin protein levels ( 29403010) Optic disc size ( 31809533) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Refractive astigmatism ( 30306274) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: NPLOC4 VPS35	8 interacting genes: CDC42 ERCC6 GZMK MAP3K1 RAF1 UBC UFD1 VPS26B
Entrez ID		112936	55666
HPRD ID		14395	06975
Ensembl ID		ENSG00000151502	ENSG00000182446
Uniprot IDs		A0A024R3L9 Q4G0F5	A0A024R8R4 Q8TAT6
PDB IDs
Enriched GO Terms of Interacting Partners?
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