VPS26B and VPS35

Data Source:
HPRD (two hybrid, in vivo)

		VPS26B	VPS35
Description		VPS26, retromer complex component B	VPS35 retromer complex component
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Cytosol Retromer Complex Retromer, Cargo-selective Complex Phagocytic Vesicle	Mitochondrion Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Extracellular Exosome Tubular Endosome Mitochondrion-derived Vesicle
	Molecular Function	Protein Binding	Protein Binding D1 Dopamine Receptor Binding
	Biological Process	Intracellular Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Cellular Response To Interferon-gamma	Intracellular Protein Transport Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Viral Process Wnt Signaling Pathway Regulation Of Macroautophagy Regulation Of Protein Stability Regulation Of Cellular Protein Metabolic Process Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Mitochondrial Fragmentation Involved In Apoptotic Process Transcytosis Negative Regulation Of Inflammatory Response Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Transport Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Negative Regulation Of Neuron Death Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Dendritic Spine Maintenance Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Presynapse Assembly Retrograde Transport, Endosome To Plasma Membrane Regulation Of Terminal Button Organization
Pathways			WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS		Verbal declarative memory ( 25648963)
Interacting Genes		2 interacting genes: NPLOC4 VPS35	12 interacting genes: APP DRD1 LINC01554 MTNR1B SLC11A2 SNX1 SNX3 VEGFA VPS26A VPS26B VPS29 ZNF512B
Entrez ID		112936	55737
HPRD ID		14395	06085
Ensembl ID		ENSG00000151502	ENSG00000069329
Uniprot IDs		A0A024R3L9 Q4G0F5	Q96QK1
PDB IDs			2R17 5F0J 5F0K 5F0L 5F0M 5F0P 5OSH 5OSI
Enriched GO Terms of Interacting Partners?
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