EIF3C and EIF3J

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		EIF3C	EIF3J
Description		eukaryotic translation initiation factor 3 subunit C	eukaryotic translation initiation factor 3 subunit J
Image
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Ribosome Binding	Translation Initiation Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Positive Regulation Of Translation Positive Regulation Of MRNA Binding	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908 21102463) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Lamb consumption ( 32066663)	Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		19 interacting genes: AAGAB ALKBH4 CALM1 EIF1AX EIF3E EIF3G EIF3J EIF3K ERCC6 HMOX2 MAPK6 NDUFA4L2 PFDN1 PLEKHF2 RPS6KA3 SMAD9 SNIP1 TACC3 TRAPPC2	15 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1
Entrez ID		8663	8669
HPRD ID		04889	04883
Ensembl ID		ENSG00000184110	ENSG00000104131
Uniprot IDs		A0A024QYU9 Q99613	A0A024R5S5 O75822
PDB IDs		3J8B 3J8C 6YBD 6YBW 6ZMW 6ZON 6ZP4 7A09	2KRB 3BPJ 6YBW 6ZMW 6ZVJ
Enriched GO Terms of Interacting Partners?
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