EIF3J and EIF3D

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		EIF3J	EIF3D
Description		eukaryotic translation initiation factor 3 subunit J	eukaryotic translation initiation factor 3 subunit D
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Translation Initiation Factor Activity Protein Binding Identical Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		15 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1	31 interacting genes: ANKRD28 BEND5 CCDC125 CCDC57 CDC42 CEP70 CREBBP DNAJB11 DVL3 EIF3G EIF3J EIF3L EIF5 ERCC6 GOLGA6L9 HOMER3 HOOK2 HSF2BP KIFC3 LZTS2 MORN3 MTUS2 PHLDA1 PICK1 POLR2G REL SAT1 TFIP11 TRIM23 TRIM27 ZRANB1
Entrez ID		8669	8664
HPRD ID		04883	04888
Ensembl ID		ENSG00000104131	ENSG00000100353
Uniprot IDs		A0A024R5S5 O75822	O15371
PDB IDs		2KRB 3BPJ 6YBW 6ZMW 6ZVJ	6YBD 6YBS 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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