EIF3J and ABCE1

Data Source:
BioGRID (two hybrid)

		EIF3J	ABCE1
Description		eukaryotic translation initiation factor 3 subunit J	ATP binding cassette subfamily E member 1
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane
	Molecular Function	Translation Initiation Factor Activity Protein Binding Identical Protein Binding	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Anti-Toxoplasma gondii IgG seropositivity ( 30610941)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1	3 interacting genes: EIF3J RNASE2 RNASEL
Entrez ID		8669	6059
HPRD ID		04883	03132
Ensembl ID		ENSG00000104131	ENSG00000164163
Uniprot IDs		A0A024R5S5 O75822	P61221
PDB IDs		2KRB 3BPJ 6YBW 6ZMW 6ZVJ	6ZME 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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