MRGBP and ACTL6A

Data Source:
HPRD (in vitro)

		MRGBP	ACTL6A
Description		MRG domain binding protein	actin like 6A
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GO Annotations	Cellular Component	Nucleoplasm NuA4 Histone Acetyltransferase Complex	Chromatin Nucleus Nucleoplasm Plasma Membrane SWI/SNF Complex Ino80 Complex Protein-containing Complex NuA4 Histone Acetyltransferase Complex NpBAF Complex
	Molecular Function	Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth	Blastocyst Formation Neural Retina Development DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Signal Transduction Nervous System Development Protein Deubiquitination Spinal Cord Development Regulation Of Growth ATP-dependent Chromatin Remodeling Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones	HATs acetylate histones RMTs methylate histone arginines UCH proteinases DNA Damage Recognition in GG-NER RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS			Pars opercularis volume ( 31530798)
Interacting Genes		25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	14 interacting genes: ARHGDIA CDK2 CDK9 EWSR1 FLII MRGBP MYC POLR2A PTEN RELA RUVBL1 SMARCA2 SMARCA4 TRRAP
Entrez ID		55257	86
HPRD ID		16646	05389
Ensembl ID		ENSG00000101189	ENSG00000136518
Uniprot IDs		Q9NV56	O96019
PDB IDs		2N1D	6LTJ
Enriched GO Terms of Interacting Partners?
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