SCARF1 and SLC7A14

Data Source:
BioGRID (two hybrid)

		SCARF1	SLC7A14
Description		scavenger receptor class F member 1	solute carrier family 7 member 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding	Protein Binding Amino Acid Transmembrane Transporter Activity
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Amino Acid Transmembrane Transport Amino Acid Transport Negative Regulation Of Phosphatase Activity
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		8578	57709
HPRD ID		06386	17222
Ensembl ID		ENSG00000074660	ENSG00000013293
Uniprot IDs		A8K6Z5 Q14162	Q8TBB6
PDB IDs
Enriched GO Terms of Interacting Partners?
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