SCARF1 and KCNJ6

Data Source:
BioGRID (two hybrid)

		SCARF1	KCNJ6
Description		scavenger receptor class F member 1	potassium inwardly rectifying channel subfamily J member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Body size at age 10 ( 32376654) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1	63 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID		8578	3763
HPRD ID		06386	02929
Ensembl ID		ENSG00000074660	ENSG00000157542
Uniprot IDs		A8K6Z5 Q14162	P48051
PDB IDs
Enriched GO Terms of Interacting Partners?
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