KCNJ6 and TNFRSF10C

Data Source:
BioGRID (two hybrid)

		KCNJ6	TNFRSF10C
Description		potassium inwardly rectifying channel subfamily J member 6	TNF receptor superfamily member 10c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex	Plasma Membrane Cell Surface Anchored Component Of Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	TRAIL-activated Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	TP53 Regulates Transcription of Death Receptors and Ligands
Drugs		Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Body size at age 10 ( 32376654) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)	Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		63 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24	34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1
Entrez ID		3763	8794
HPRD ID		02929	04681
Ensembl ID		ENSG00000157542	ENSG00000173535
Uniprot IDs		P48051	O14798
PDB IDs
Enriched GO Terms of Interacting Partners?
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