PIAS1 and SP3

  • Data Source:
  • HPRD (two hybrid, in vitro)

PIAS1

SP3

Description protein inhibitor of activated STAT 1 Sp3 transcription factor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Diverticular disease ( 30177863)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Major depressive disorder ( 23377640)
  • Number of twin births ( 30760885)
Interacting Genes 107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76 29 interacting genes: AKT1 CIB3 E2F1 EP300 ESR1 GABPA GCH1 GRIN1 HDAC1 HDAC2 HLTF LIN54 NKX3-1 PHF21A PIAS1 POGZ RB1 RBBP4 RPS20 SNRPB SP1 SPANXN2 STK19 SUMO1 TP53 TP73 UBE2I VEGFA ZBTB7A
Entrez ID 8554 6670
HPRD ID 16029 03483
Ensembl ID ENSG00000033800 ENSG00000172845
Uniprot IDs O75925 Q1XBU8 B7ZLN9 Q02447 Q59FX5 Q86TP0
PDB IDs 1V66
Enriched GO Terms of Interacting Partners?
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